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What is a Nucleotide Sugar?

What do we offer?

Nucleotide sugars are high-energy compounds. They are used for a variety of applications like the synthesis of human milk oligosaccharides, specialty carbohydrates and glycans on therapeutic proteins.  Up to now, they are scarcely available at costs of 3 – 100 € per milligram and only in small amounts. 

Nucleotide sugar sketch

Our technology allows the production of nucleotide sugars for affordable prices. By using highly efficient multi-enzyme cascades, we can synthesize nucleotides sugars from inexpensive substrates. Our goal is to make them available for diverse applications in food and pharma. Our synthesis process is scalable and protected by our IP portfolio.

Nucleotide Sugar Pipeline




UDP N D.png



CMP-N-acetylneuraminic acid



Rexer TFT et al. 
Cell-Free Multi-Enzyme Synthesis and Purification of Uridine Diphosphate Galactose.

Rexer TFT et al. 
Multi-enzyme Cascades for the In Vitro Synthesis of Guanosine Diphosphate L-Fucose

Rexer TFT et al.
Enzymatic Synthesis of Glycans and Glycoconjugates

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