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What is an activated sugar?

Activated sugars are high-energy compounds that build glycans. Theoretically, these building blocks could be used for various applications like synthesizing human milk oligosaccharides, specialty carbohydrates, and glycans on therapeutic proteins. However, the fact that they are offered by existing suppliers at prices of up to €2,500 per gram has made many supposed applications not commercially feasible. 

Nucleotide sugar sketch

What do we offer?

Our patented technology allows the production of activated sugars at a fraction of the existing suppliers' prices. By using highly efficient multi-enzyme cascades, we can synthesize activated sugars from inexpensive substrates. Our goal is to make them available for diverse applications in food and pharma, including novel complex human milk oligosaccharides and modifying antibodies' glycosylation efficiently. All enzymes are also produced in-house cheaply simultaneously in one strain, making it favorable from a regulatory perspective. Our synthesis processes are scalable and protected by our IP portfolio.

eversyn portfolio

Activated Sugar Pipeline

GDP fucose



UDP glucasamine



CMP-N-acetylneuraminic acid

UDP galactose


Rexer TFT et al. 
Cell-Free Multi-Enzyme Synthesis and Purification of Uridine Diphosphate Galactose.

Rexer TFT et al. 
Multi-enzyme Cascades for the In Vitro Synthesis of Guanosine Diphosphate L-Fucose

Rexer TFT et al.
Enzymatic Synthesis of Glycans and Glycoconjugates

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