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What is an activated sugar?

Activated sugars are high-energy compounds. They are used for a variety of applications like the synthesis of human milk oligosaccharides, specialty carbohydrates and glycans on therapeutic proteins.  Up to now, they are scarcely available at costs of 3 – 100 € per milligram and only in small amounts. 

Nucleotide sugar sketch

What do we offer?

Our technology allows the production of activated sugars for affordable prices. By using highly efficient multi-enzyme cascades, we can synthesize activated sugars from inexpensive substrates. Our goal is to make them available for diverse applications in food and pharma. Our synthesis process is scalable and protected by our IP portfolio.

eversyn portfolio

Activated Sugar Pipeline

GDP fucose

GDP-L-fucose

UDP-α-D-galactose

UDP glucasamine

UDP-N-acetyl-D-glucosamine

CMP.png

CMP-N-acetylneuraminic acid

UDP galactose

Publications

Rexer TFT et al. 
Cell-Free Multi-Enzyme Synthesis and Purification of Uridine Diphosphate Galactose.
https://doi.org/10.1002/cbic.202100361

Rexer TFT et al. 
Multi-enzyme Cascades for the In Vitro Synthesis of Guanosine Diphosphate L-Fucose
https://doi.org/10.1002/cctc.202001854

Rexer TFT et al.
Enzymatic Synthesis of Glycans and Glycoconjugates
https://doi.org/10.1007/10_2020_148

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