Until 31.12.2024: Save 30% on your first order with code: eversyn30
What is an activated sugar?
Activated sugars are high-energy compounds crucial for various applications, including the synthesis of human milk oligosaccharides, specialty carbohydrates, and glycans on therapeutic proteins. Despite their importance, these compounds have been scarce and prohibitively expensive. This scarcity and high cost has presented significant challenges for advancing studies and production processes that rely on these vital compounds.
What do we offer?
Our technology allows the production of activated sugars for affordable prices. We can synthesize activated sugars from inexpensive substrates using highly efficient multi-enzyme cascades. Our goal is to make them available for diverse applications in food and pharma. Our cell-free synthesis process is robust and scalable.
Currently available:
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UDP-α-D-galactose
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UDP-N-acetyl-D-glucosamine
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CMP-N-acetylneuraminic acid
Our pipeline:
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GDP-L-fucose
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UDP-N-acetyl-D-galactosamine
Publications
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Rexer TFT et al. Cell-Free Multi-Enzyme Synthesis and Purification of Uridine Diphosphate Galactose. https://doi.org/10.1002/cbic.202100361
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Rexer TFT et al. Multi-enzyme Cascades for the In Vitro Synthesis of Guanosine Diphosphate L-Fucose. https://doi.org/10.1002/cctc.202001854
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Rexer TFT et al. Enzymatic Synthesis of Glycans and Glycoconjugates. https://doi.org/10.1007/10_2020_148