CMP-N-Acetylneuraminic Acid

Description

CMP-Neu5Ac is a nucleotide sugar consisting of cytidine 5'-monophospho-N-acetylneuraminic acid, a phosphate-bound form of sialic acid. Nucleotide sugars are the activated forms of monosaccharides required for cellular metabolism and biosynthesis reactions. CMP-Neu5Ac serves as a donor substrate for sialyltransferases in the biosynthesis of sialic acid-containing glycans.

Appearance

Lyophilized white powder

Purity

≥ 90% (HPLC-UV). Product has not been tested for endotoxins

Solubility

Clear (> 50 mg/mL, H2O)

Storage

At -20°C.

Special instructions

For research use only! Intended use for in vitro laboratory applications.

Toxicity & Safety

Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008.

Selected References

Rexer, T.;  Laaf, D.;  Gottschalk, J.;  Frohnmeyer, H.;  Rapp, E.; Elling, L., Enzymatic Synthesis of Glycans and Glycoconjugates. In Advances in Biochemical Engineering/Biotechnology, 2021; Vol. 175, pp 231-280.