alpha-1,6-fucosidase

The product provides the user with a bacterial α-1,6-fucosidase (α1,6Fuc) expressed in E. coli for the defucosylation of glycans:

• Free N-glycans: The α1,6Fuc catalysis the hydrolysis of the core α-1,6-fucose from Man3F. The enzyme has limited activity on complex glycans.
• Glycoproteins: The α1,6Fuc catalysis the cleavage of α-1,6-fucose linked to GlcNAc residues on glycoproteins such as IgG with limited activity/yield. The α1,6Fuc has no activity on glycoproteins with complex or mannosylated glycans.

The enzyme is for research use only. Not for use in diagnostic procedures.

The product is available only upon request.

Pack size: 50EqU / 500EqU 

Equivalent Unit (EqU) definition: Is the amount of enzyme required to achieve complete conversion of 3 pmol of Man3F to Man3 in 24 h at 37 °C.