UDP-GalNAc

Description

UDP-GalNAc is a nucleotide sugar consisting of the nucleotide uridine 5'-diphosphate and a phosphate-bound monosaccharide, N-acetylgalactosamine. Nucleotide sugars are the activated forms of monosaccharides required for cellular metabolism and biosynthesis reactions. UDP-GalNAc serves as a donor substrate for N-acetylgalactosaminyltransferases in the biosynthesis of N-acetylgalactosamine-containing glycans and oligosaccharides.

Appearance

Lyophilized white powder, hygroscopic

Purity

≥ 90 % (HPLC-UV); Product has not been tested for endotoxins.

Solubility

Clear (>50 mg/ml, H2O)

Storage

At -20°C

Special instructions

For research use only! Intended use for in vitro laboratory applications.

Toxicity & Safety

Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008

Selected References

Rexer, T.; Laaf, D.; Gottschalk, J.; Frohnmeyer, H.; Rapp, E.; Elling, L., Enzymatic Synthesis of Glycans and Glycoconjugates. In Advances in Biochemical Engineering/Biotechnology, 2021; Vol. 175, pp 231-280.

Hoang, S. -T.;  Wormstall S. -T.; Hoang N. -H.; Reichl U.; Rexer T., Establishment of a Cell-Free Multi-Enzyme Cascade for the Synthesis of UDP-GalNAc, New Biotechnology, 2025, ISSN 1871-6784, https://doi.org/10.1016/j.nbt.2025.05.003.