GDP-fucose

Description

GDP-fucose is a nucleotide sugar consisting of the nucleotide guanosine 5'-diphosphate and a phosphate-bound monosaccharide, L-fucose. Nucleotide sugars are the activated forms of monosaccharides required for cellular metabolism and biosynthesis reactions. GDP-fucose serves as a donor substrate for fucosyltransferases in the biosynthesis of fucose-containing glycans and oligosaccharides.

Appearance

Lyophilized white powder

Purity

≥ 90% (HPLC-UV). Product has not been tested for endotoxins

Solubility

Clear (> 50 mg/mL, H2O)

Storage

At -20°C.

Special instructions

For research use only! Intended use for in vitro laboratory applications.

Toxicity & Safety

Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008.

Selected References

Rexer, T.;  Laaf, D.;  Gottschalk, J.;  Frohnmeyer, H.;  Rapp, E.; Elling, L., Enzymatic Synthesis of Glycans and Glycoconjugates. In Advances in Biochemical Engineering/Biotechnology, 2021; Vol. 175, pp 231-280.